SCHEMBL5789348

SCHEMBL5789348

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nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 10/20 0.47
ALOX15 P16050 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
KMT2A Q03164 1/20 0.47
ARG1 P05089 1/20 0.43
DPP7 Q9UHL4 9/20 0.40
DPP8 Q6V1X1 4/20 0.36
DPP9 Q86TI2 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5790371 1.00 DPP4 (0.47) DPP4ALOX15BLMPMP22KMT2A
SCHEMBL5790370 1.00 DPP4 (0.47) DPP4ALOX15BLMPMP22KMT2A
SCHEMBL5788342 0.82 ALOX15 (0.47) DPP4ALOX15BLMPMP22KMT2A
SCHEMBL5791271 0.81 DPP4 (0.54) DPP4ALOX15BLMPMP22KMT2A
SCHEMBL6738000 0.81 DPP4 (0.54) DPP4ALOX15BLMPMP22KMT2A
SCHEMBL6389329 0.81 DPP4 (0.46) DPP4ALOX15BLMPMP22KMT2A
Hydrochloric Acid SCHEMBL6388075 0.79 DPP4 (0.45) DPP4ALOX15BLMPMP22KMT2A
SCHEMBL1072126 0.78 ALOX15 (0.50) DPP4ALOX15BLMPMP22KMT2A
SCHEMBL1509740 0.78 ALOX15 (0.50) DPP4ALOX15BLMPMP22KMT2A
SCHEMBL6742082 0.76 DPP7 (0.50) DPP4ALOX15BLMPMP22KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1622870-A2 GLUTAMINYL BASED DP IV-INHIBITORS Prosidion Ltd. (GB) 2006-02-08 EP disclosed
WO-2004099134-A2 GLUTAMINYL BASED DP IV-INHIBITORS PROSIDION LTD. (GB) 2004-11-18 WO disclosed
US-20040229848-A1 Glutaminyl based DP IV-inhibitors PROSIDION LIMITED (GB) 2004-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040229848-A1 Glutaminyl based DP IV-inhibitors DPP4, DPP3, DNPEP DPP4 1/4885ALOX15 4131/4885BLM 3796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.