Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850903 | 0.82 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL10768107 | 0.80 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL10763115 | 0.80 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL10763104 | 0.80 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL2852773 | 0.80 | RAB9A (0.69) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL19380438 | 0.77 | HPGDS (0.64) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL7591232 | 0.77 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL4028151 | 0.77 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL4028148 | 0.77 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL2848793 | 0.76 | MAPT (0.54) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685092-A2 | ASYMMETRIC REDUCTIVE AMINATION OF KETO ACID DERIVATIVES FOR PRODUCING AMINO ACID DERIVATIVES | Takasago International Corporation (JP) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005028419-A2 | ASYMMETRIC REDUCTIVE AMINATION OF KETO ACID DERIVATIVES FOR PRODUCING AMINO ACID DERIVATIVES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-03-31 | — | — | WO | disclosed |