Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868320 | 0.76 | HCAR2 (0.42) | RETMEN1KMT2AEGFR | |
| SCHEMBL5792325 | 0.74 | RET (0.33) | RETMEN1KMT2AEGFR | |
| SCHEMBL5789842 | 0.71 | — | — | |
| SCHEMBL24130013 | 0.71 | ALDH1A1 (0.39) | MEN1KMT2AEGFR | |
| SCHEMBL3770253 | 0.71 | NOTUM (0.42) | RETMEN1KMT2AEGFR | |
| SCHEMBL5788631 | 0.71 | RET (0.32) | RETMEN1KMT2AEGFR | |
| SCHEMBL1807534 | 0.71 | ALDH1A1 (0.43) | MEN1KMT2AEGFR | |
| SCHEMBL3771801 | 0.69 | EGFR (0.33) | RETMEN1KMT2AEGFR | |
| SCHEMBL13060542 | 0.67 | HCRTR2 (0.31) | — | |
| SCHEMBL5790591 | 0.67 | RET (0.34) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1704143-A1 | MALONONITRILE COMPOUND AS PESTICIDES | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |
| WO-2005068432-A1 | MALONONITRILE COMPOUND AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-07-28 | — | — | WO | disclosed |