Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 7/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790106 | 0.78 | ALDH1A1 (0.46) | HCRTR2HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL6415460 | 0.76 | HCRTR1 (0.48) | HCRTR2HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL5791691 | 0.76 | HCRTR2 (0.57) | HCRTR2HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL11560499 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPK1HTT | |
| SCHEMBL24016912 | 0.74 | HCRTR2 (0.54) | HCRTR2HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL20563461 | 0.74 | HTT (0.52) | HCRTR1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL24522228 | 0.74 | HCRTR2 (0.54) | HCRTR2HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL6503140 | 0.73 | MEN1 (0.45) | HCRTR1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL2656268 | 0.73 | MAPT (0.50) | HCRTR1MEN1KMT2AUSP2MAPK1 | |
| SCHEMBL6494948 | 0.71 | FNTA (0.45) | HCRTR1ALDH1A1MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006003277-A1 | AROMATIC BIARYL PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE AS MEDICINES | AVENTIS PHARMA S.A. (FR) | 2006-01-12 | — | — | WO | claimed |