Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5788590 | 0.83 | ALDH1A1 (0.67) | ALDH1A1TSHRKMT2AMEN1LMNA | |
| SCHEMBL6503140 | 0.82 | MEN1 (0.45) | ALDH1A1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL6495297 | 0.81 | KDM4E (0.48) | TSHRKMT2AUSP2MEN1LMNA | |
| SCHEMBL5789223 | 0.78 | HCRTR2 (0.48) | ALDH1A1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL20563461 | 0.77 | HTT (0.52) | ALDH1A1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL6415460 | 0.76 | HCRTR1 (0.48) | ALDH1A1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL6411953 | 0.76 | SCD (0.41) | ALDH1A1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL6494948 | 0.73 | FNTA (0.45) | ALDH1A1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL2656268 | 0.73 | MAPT (0.50) | KMT2AUSP2MEN1MAPTMAPK1 | |
| SCHEMBL6262316 | 0.73 | TSHR (0.52) | ALDH1A1TSHRKMT2AUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006003277-A1 | AROMATIC BIARYL PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE AS MEDICINES | AVENTIS PHARMA S.A. (FR) | 2006-01-12 | — | — | WO | claimed |