SCHEMBL578932

SCHEMBL578932

CN1C(C)(C)CC(=O)CC1(C)C

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9717101 0.97 GAA (0.34) GAAMEN1KMT2ATSHRNFKB1
Iodide SCHEMBL6292630 0.97 GAA (0.34) GAAMEN1KMT2ATSHRNFKB1
Hydrochloric Acid SCHEMBL11333509 0.97 GAA (0.34) GAAMEN1KMT2ATSHRNFKB1
Acetic Acid SCHEMBL984620 0.88 TSHR (0.39) GAAMEN1KMT2ATSHRNFKB1
Tetrahydrofuran SCHEMBL6024003 0.84 ALDH1A1 (0.33)
SCHEMBL15071294 0.83 TSHR (0.35) TSHRNFKB1CYP2C19
SCHEMBL13629764 0.79 KDM4E (0.34) TSHRCYP2C19
Nitrilotriacetic Acid SCHEMBL986873 0.78 TSHR (0.37) GAAMEN1KMT2ATSHRNFKB1
SCHEMBL50791 0.77 GAA (0.39) GAAMEN1KMT2A
Hydrochloric Acid SCHEMBL20704048 0.77 GAA (0.35) GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677565-A Preparation method of hindered amine light stabilizer intermediate 南通大学 2023-02-03 CN claimed
CN-112239458-A Hindered amine light stabilizer intermediate and preparation method of hindered amine light stabilizer 利安隆(天津)新材料科技有限公司 2021-01-19 CN claimed
CN-112126141-A Preparation method of rubber material with high aging resistance 东莞市万里行橡胶有限公司 2020-12-25 CN claimed
CN-107674019-B Synthetic method of 1,2,2,6, 6-pentamethyl-4-piperidone 宿迁市振兴化工有限公司 2020-09-15 CN claimed
CN-111116457-A Green synthesis method of 1,2,2,6, 6-pentamethyl-4-piperidone 宿迁联盛科技股份有限公司 2020-05-08 CN claimed
CN-110950794-A Preparation method of 1,2,2,6, 6-pentamethyl-4-piperidone 宿迁联盛科技股份有限公司 2020-04-03 CN claimed
CN-107674019-A A kind of synthetic method of the piperidones of 1,2,2,6,6 pentamethyl 4 宿迁市振兴化工有限公司 2018-02-09 CN claimed
US-7862746-B2 Stabilization of natural composites BASF SE. (DE) 2011-01-04 US claimed
US-20060183821-A1 Stabilization of natural composites CIBA CORPORATION 2006-08-17 US claimed
US-5945536-A Continuous process for preparing 4-aminopiperidines HUELS ATIENGESELLSCHAFT (DE) 1999-08-31 US claimed
EP-0729947-A1 Process for the methylation of 2,2,6,6-tetramethylpiperidin-4-one CIBA-GEIGY AG (CH) 1996-09-04 EP claimed
JP-8245588-A None JP disclosed
US-20250206884-A1 ULTRAVIOLET RADIATION-CURABLE POLYSILOXANE COMPOSITION, AND DAMPING MATERIAL TAICA CORPORATION (JP) 2025-06-26 US disclosed
US-20250011287-A1 FLUORINE-CONTAINING COMPOUND AND CONTRAST AGENT TDK CORPORATION (JP) 2025-01-09 US disclosed
US-20240173439-A1 FLUORINE-CONTAINING COMPOUND AND CONTRAST MEDIUM TDK CORPORATION (JP) 2024-05-30 US disclosed
WO-1981001706-A1 NOVEL SECONDARY AND TERTIARY AMINES AND THE USE THEREOF IN COMPOSITIONS AND IN STABILIZATION OF POLYMERS AGAINST ULTRAVIOLET LIGHT DEGRADATION GOODRICH CO B F (US) 1981-06-25 WO disclosed
EP-0013665-A1 Polymeric polyamino 1,3,5-triazines containing at least one polyalkylpiperidine group, their preparation, their use in stabilizing an organic material and the material stabilized therewith CIBA-GEIGY AG (CH) 1980-07-23 EP disclosed
US-4208525-A TETRAALKYL PYRIDINES OR N-ALKYL DERIVATIVES BY CATALYTIC HYDROGENATION IN AN ACID MEDIUM CIBA-GEIGY CORPORATION (US) 1980-06-17 US disclosed
US-4070461-A ANTICHOLESTEROL MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-01-24 US disclosed
US-4046736-A 1,3-BIS[(2,2,6,6-Tetraalkyl-4-piperidylidene)amino]guanidines as light stabilizers for polyolefins AMERICAN CYANAMID COMPANY (US) 1977-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011287-A1 FLUORINE-CONTAINING COMPOUND AND CONTRAST AGENT AFF1, AFF2, ZRANB2 GAA 3894/4885MEN1 117/4885KMT2A 1168/4885
US-20240173439-A1 FLUORINE-CONTAINING COMPOUND AND CONTRAST MEDIUM AFF1, AFF2, AFF4 GAA 4405/4885MEN1 6/4885KMT2A 3192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.