SCHEMBL13629764

SCHEMBL13629764

CCC1(CC)CC(=O)CC(C)(C)N1C

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
CYP2C19 P33261 1/20 0.34
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13414741 0.87 KDM4E (0.34) KDM4ELMNACYP2C19TSHRNPSR1
SCHEMBL578932 0.79 GAA (0.35) CYP2C19TSHR
SCHEMBL23354654 0.78 KDM4E (0.33) KDM4ELMNACYP2C19TSHRNPSR1
SCHEMBL9717101 0.77 GAA (0.34) CYP2C19TSHR
Hydrochloric Acid SCHEMBL11333509 0.77 GAA (0.34) CYP2C19TSHR
Iodide SCHEMBL6292630 0.77 GAA (0.34) CYP2C19TSHR
SCHEMBL15069995 0.75 KDM4E (0.31) KDM4ELMNACYP2C19
SCHEMBL15071286 0.73
SCHEMBL3676473 0.73 KDM4E (0.34) KDM4ELMNACYP2C19TSHRNPSR1
SCHEMBL3676476 0.71 KDM4E (0.33) KDM4ELMNACYP2C19TSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8557927-B2 Comb-shaped graft copolymers and methods of manufacturing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-10-15 US disclosed
US-20130165592-A1 COMB-SHAPED GRAFT COPOLYMERS AND METHODS OF MANUFACTURING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-06-27 US disclosed
US-7619050-B2 Alkoxyamines containing a radically polymerizable group CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-11-17 US disclosed
US-7619050-B2 Alkoxyamines containing a radically polymerizable group CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-11-17 US disclosed
EP-1749032-B1 ALKOXYAMINES CONTAINING A RADICALLY POLYMERIZABLE GROUP CIBA SC HOLDING AG (CH) 2008-02-27 EP disclosed
US-20070232768-A1 Alkoxyamines Containing a Radically Polymerizable Group CIBA SPECIALTY CHEMICALS CORP. 2007-10-04 US disclosed
US-20070232768-A1 Alkoxyamines Containing a Radically Polymerizable Group CIBA SPECIALTY CHEMICALS CORP. 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232768-A1 Alkoxyamines Containing a Radically Polymerizable Group ALKBH3, ALKBH2, ALKBH5 KDM4E 173/4885LMNA 2225/4885CYP2C19 1662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.