Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.51 |
| ▸ | MAOB | P27338 | 10/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5789323 | 1.00 | MAOA (0.51) | MAOAMAOBNPC1RAB9APOLB | |
| SCHEMBL5788483 | 0.84 | MAOB (0.54) | MAOAMAOBNPC1RAB9AL3MBTL1 | |
| SCHEMBL5788481 | 0.84 | MAOB (0.54) | MAOAMAOBNPC1RAB9AL3MBTL1 | |
| SCHEMBL3450504 | 0.79 | MAOA (0.54) | MAOAMAOBNPC1RAB9APOLB | |
| SCHEMBL3450500 | 0.79 | MAOA (0.54) | MAOAMAOBNPC1RAB9APOLB | |
| SCHEMBL13110402 | 0.78 | MAOA (0.48) | MAOAMAOBNPC1RAB9APOLB | |
| SCHEMBL5787402 | 0.77 | KDM4E (0.45) | NPC1RAB9AL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL5787405 | 0.77 | KDM4E (0.45) | NPC1RAB9AL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL5788075 | 0.74 | FFAR1 (0.47) | MAOAMAOBNPC1RAB9APOLB | |
| SCHEMBL3450014 | 0.73 | FFAR1 (0.53) | MAOAMAOBNPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060258722-A1 | Condensed ring compound | TAKEDA PHARMACEUTICAL COMPANY., LTD. (JP) | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258722-A1 | Condensed ring compound | GPR119, GLP1R, GCGR | MAOA 4002/4885MAOB 3684/4885NPC1 2765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.