Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 12/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10706616 | 1.00 | HTT (0.38) | HTTCCR2KDM4EALDH1A1 | |
| SCHEMBL18077368 | 0.94 | L3MBTL1 (0.38) | HTTCCR2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL320459 | 0.92 | L3MBTL1 (0.37) | HTTCCR2KDM4EALDH1A1 | |
| SCHEMBL10707479 | 0.91 | HTT (0.36) | HTTCCR2KDM4EALDH1A1 | |
| SCHEMBL9450933 | 0.89 | SIGMAR1 (0.40) | HTTCCR2 | |
| SCHEMBL318758 | 0.88 | — | — | |
| SCHEMBL1579752 | 0.88 | — | — | |
| SCHEMBL17144672 | 0.85 | L3MBTL1 (0.35) | HTTCCR2KDM4EALDH1A1 | |
| SCHEMBL17144305 | 0.85 | L3MBTL1 (0.35) | HTTCCR2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4200469 | 0.84 | HTT (0.38) | HTTCCR2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633348-A1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | Elan Pharmaceuticals, Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004098589-A1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARMACEUTICALS, INC. (US) | 2004-11-18 | — | — | WO | disclosed |