Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 8/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 8/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12250931 | 0.73 | GGPS1 (0.56) | GGPS1SLC16A3SLC16A1RXRARXRB | |
| SCHEMBL10534532 | 0.72 | PDK2 (0.45) | PDK2 | |
| SCHEMBL5790549 | 0.70 | TAAR1 (0.38) | KDM4EMAPT | |
| SCHEMBL5788933 | 0.70 | ESR2 (0.38) | — | |
| SCHEMBL12251037 | 0.69 | CLK4 (0.62) | GGPS1SLC16A3SLC16A1RXRARXRB | |
| SCHEMBL12251038 | 0.68 | KIF11 (0.51) | GGPS1RXRARXRB | |
| SCHEMBL5788540 | 0.67 | APP (0.40) | KDM4EMAPT | |
| SCHEMBL12251033 | 0.67 | PRMT6 (0.48) | MAPT | |
| SCHEMBL12251040 | 0.67 | BACE1 (0.47) | GGPS1 | |
| SCHEMBL12251032 | 0.67 | PRMT6 (0.48) | GGPS1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660500-A1 | SUBSTITUTED IMIDAZOPYRIMIDINES FOR THE PREVENTION AND TREATMENT OF CANCER | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005014598-A1 | SUBSTITUTED IMIDAZOPYRIMIDINES FOR THE PREVENTION AND TREATMENT OF CANCER | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2005-02-17 | — | — | WO | disclosed |