Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20066493 | 0.78 | HDAC8 (0.33) | — | |
| SCHEMBL23212683 | 0.72 | NPC1 (0.37) | — | |
| SCHEMBL13970839 | 0.70 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31044609 | 0.70 | CYP1A1 (0.30) | — | |
| SCHEMBL13958713 | 0.70 | PDK2 (0.33) | — | |
| SCHEMBL590849 | 0.69 | KDM4E (0.34) | MEN1KMT2ASMN1; SMN2 | |
| Diethylamine SCHEMBL27864804 | 0.68 | MAP2K1 (0.33) | — | |
| SCHEMBL578421 | 0.67 | PYCR1 (0.46) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22979994 | 0.66 | HDAC8 (0.37) | — | |
| SCHEMBL28097817 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556071-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | University Health Network (CA) | 2013-02-13 | — | — | EP | disclosed |
| EP-2417127-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | University Health Network (CA) | 2012-02-15 | — | — | EP | disclosed |
| WO-2011123946-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |
| WO-2010115279-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2010-10-14 | — | — | WO | disclosed |