Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20066493 | 0.77 | HDAC8 (0.33) | CYP1A1CYP1B1 | |
| SCHEMBL13958713 | 0.77 | PDK2 (0.33) | CYP1A1CYP1B1 | |
| SCHEMBL603677 | 0.77 | TTR (0.37) | — | |
| SCHEMBL590849 | 0.72 | KDM4E (0.34) | — | |
| SCHEMBL189364 | 0.72 | RAPGEF4 (0.33) | — | |
| SCHEMBL2782697 | 0.72 | CES2 (0.36) | CYP1A1CYP1B1 | |
| SCHEMBL23212683 | 0.71 | NPC1 (0.37) | — | |
| SCHEMBL601770 | 0.70 | DGAT1 (0.31) | — | |
| SCHEMBL9793646 | 0.70 | CYP1A1 (0.34) | CYP1A1CYP1B1 | |
| SCHEMBL578952 | 0.70 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285873-B | RET inhibitor, pharmaceutical composition thereof and application thereof | 广东东阳光药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-111285874-B | RET inhibitor, pharmaceutical composition thereof and application thereof | 广东东阳光药业股份有限公司 | 2024-08-09 | — | — | CN | disclosed |