Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 18/20 | 0.43 |
| ▸ | KDR | P35968 | 10/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5788683 | 0.87 | USP7 (0.48) | TGFBR1KDRMAPK14GAAMAPT | |
| SCHEMBL5791586 | 0.86 | TGFBR1 (0.59) | TGFBR1KDRMAPK14RIPK2GAA | |
| SCHEMBL5791351 | 0.85 | TGFBR1 (0.44) | TGFBR1KDRMAPK14RIPK2 | |
| SCHEMBL5788266 | 0.83 | TGFBR1 (0.43) | TGFBR1KDRMAPK14RIPK2GAA | |
| SCHEMBL5786493 | 0.81 | HRH3 (0.44) | TGFBR1KDRMAPK14GAAMAPT | |
| SCHEMBL5790314 | 0.81 | TGFBR1 (0.46) | TGFBR1KDRMAPK14MAPT | |
| SCHEMBL5790966 | 0.81 | TGFBR1 (0.44) | TGFBR1KDRMAPK14RIPK2GAA | |
| SCHEMBL5792126 | 0.81 | GAA (0.42) | TGFBR1KDRMAPK14GAAMAPT | |
| SCHEMBL5790863 | 0.79 | TGFBR1 (0.42) | TGFBR1KDRMAPK14RIPK2GAA | |
| SCHEMBL5789395 | 0.79 | TGFBR1 (0.48) | TGFBR1KDRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1543003-B1 | IMIDAZO¬1,2-A|PYRIDINES | SMITHKLINE BEECHAM CORP (US) | 2006-05-17 | — | — | EP | disclosed |
| US-20050234029-A1 | Compounds | DODIC NERINA | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234029-A1 | Compounds | SMAD3, SMAD2, ACVR1 | TGFBR1 4/4885KDR 160/4885MAPK14 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.