Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10535805 | 0.98 | MAOB (0.54) | MAOAGRIK1MAOBHTR2AIDO1 | |
| SCHEMBL3266047 | 0.86 | S1PR2 (0.59) | MAOAGRIK1MAOBHTR2AIDO1 | |
| SCHEMBL829786 | 0.85 | ANPEP (0.55) | MAOAMAOBHTR2AIDO1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1979100 | 0.84 | S1PR2 (0.57) | MAOAGRIK1MAOBHTR2AIDO1 | |
| Bromide SCHEMBL10928757 | 0.83 | SIGMAR1 (0.50) | MAOAMAOBHTR2AIDO1SIGMAR1 | |
| SCHEMBL29017813 | 0.82 | HTR2A (0.57) | MAOAHTR2ASIGMAR1 | |
| SCHEMBL3712834 | 0.82 | SLC6A2 (0.56) | MAOAGRIK1MAOBHTR2ASIGMAR1 | |
| SCHEMBL29029777 | 0.82 | MAOA (0.50) | MAOAGRIK1MAOBHTR2AIDO1 | |
| SCHEMBL14544283 | 0.82 | GRIK1 (0.54) | MAOAGRIK1MAOBHTR2AIDO1 | |
| SCHEMBL456442 | 0.82 | GRIK1 (0.54) | MAOAGRIK1MAOBHTR2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633348-A1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | Elan Pharmaceuticals, Inc. (US) | 2006-03-15 | — | — | EP | claimed |
| WO-2004098589-A1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARMACEUTICALS, INC. (US) | 2004-11-18 | — | — | WO | claimed |