Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Eticyclidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Eticyclidine SCHEMBL8452334 | 0.90 | GRIN2D (0.49) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| Eticyclidine SCHEMBL7258514 | 0.90 | GRIN2D (0.51) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| Eticyclidine SCHEMBL66697 | 0.86 | GRIN2D (0.57) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| Eticyclidine SCHEMBL10669385 | 0.85 | GRIN2D (0.58) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL23497375 | 0.82 | ALDH1A1 (0.44) | OPRM1POLBTSHRALDH1A1GAA | |
| SCHEMBL469195 | 0.78 | OPRM1 (0.48) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL28391948 | 0.75 | GRIN2D (0.56) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| Hydrochloric Acid SCHEMBL28391331 | 0.74 | GRIN2D (0.57) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL30534232 | 0.73 | GRIN2D (0.62) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL28389473 | 0.73 | GRIN2D (0.48) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006002408-A1 | TARNISH RESISTANT COMPOSITIONS AND METHODS OF USING SAME | STERIDYNE LABORATORIES, INC. (US) | 2006-01-05 | — | — | WO | disclosed |
| US-20050287316-A1 | Tarnish resistant compositions and methods of using same | STERIDYNE LABORATORIES, INC. | 2005-12-29 | — | — | US | disclosed |
| EP-0311361-B1 | CORROSION INHIBITION | AT&T Corp. (US) | 1992-07-08 | — | — | EP | disclosed |
| US-4944916-A | Corrosion inhibition | AT&T BELL LABORATORIES (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0311361-A2 | Corrosion inhibition | AT&T Corp. (US) | 1989-04-12 | — | — | EP | disclosed |