Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 15/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 15/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 15/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388057 | 0.89 | CACNA1G (0.49) | CACNA1GCACNA1HCACNA1ICYP2D6CHRM2 | |
| SCHEMBL7375950 | 0.89 | CACNA1G (0.49) | CACNA1GCACNA1HCACNA1ICYP2D6CHRM2 | |
| SCHEMBL4399774 | 0.71 | CACNA1G (0.54) | CACNA1GCACNA1HCACNA1ICHRM2CHRM1 | |
| SCHEMBL4399779 | 0.71 | CACNA1G (0.54) | CACNA1GCACNA1HCACNA1ICHRM2CHRM1 | |
| SCHEMBL18425663 | 0.61 | CACNA1G (0.50) | CACNA1GCACNA1HCACNA1I | |
| SCHEMBL20241880 | 0.61 | KDM4E (0.46) | ALDH1A1 | |
| SCHEMBL22506821 | 0.61 | CACNA1G (0.50) | CACNA1GCACNA1HCACNA1I | |
| SCHEMBL20241734 | 0.60 | HTR6 (0.64) | — | |
| SCHEMBL21378870 | 0.60 | HTR6 (0.48) | ALDH1A1 | |
| SCHEMBL20242020 | 0.59 | HTR6 (0.50) | CYP2D6ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051176-B1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARMA INC (US) | 2006-11-22 | — | — | EP | disclosed |