Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A1 | P53985 | 20/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4803426 | 0.88 | SLC16A1 (0.84) | SLC16A1CYP2C9CYP3A4 | |
| SCHEMBL5788605 | 0.86 | SLC16A1 (0.49) | SLC16A1CYP2C9CYP3A4 | |
| SCHEMBL5789937 | 0.83 | SLC16A1 (0.60) | SLC16A1CYP2C9CYP3A4 | |
| SCHEMBL5791636 | 0.83 | SLC16A1 (0.63) | SLC16A1CYP2C9CYP3A4 | |
| SCHEMBL5788474 | 0.82 | SLC16A1 (0.51) | SLC16A1CYP2C9CYP3A4 | |
| SCHEMBL6345554 | 0.82 | SLC16A1 (0.75) | SLC16A1CYP2C9 | |
| SCHEMBL5790956 | 0.81 | SLC16A1 (0.46) | SLC16A1CYP2C9CYP3A4 | |
| SCHEMBL4802041 | 0.81 | SLC16A1 (0.82) | SLC16A1CYP2C9CYP3A4 | |
| SCHEMBL6340735 | 0.80 | SLC16A1 (0.73) | SLC16A1CYP2C9CYP3A4 | |
| SCHEMBL6355148 | 0.80 | SLC16A1 (0.69) | SLC16A1CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412362-B1 | THIENO¬2,3-d|PYRIMIDINEDIONES AS INHIBITORS OF T-CELLS PROLIFERATION | ASTRAZENECA AB (SE) | 2006-08-02 | — | — | EP | claimed |