Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5854971 | 0.67 | HDAC3 (0.32) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL9145384 | 0.65 | HDAC3 (0.52) | TP53HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL5855556 | 0.65 | HDAC3 (0.30) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL2118348 | 0.65 | HDAC3 (0.30) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL6690484 | 0.61 | TP53 (0.36) | TP53HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL4940713 | 0.59 | HPGD (0.31) | — | |
| SCHEMBL8162945 | 0.58 | — | — | |
| SCHEMBL4823777 | 0.56 | — | — | |
| SCHEMBL1643947 | 0.55 | HDAC3 (0.63) | TP53HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6634673 | 0.55 | HDAC3 (0.63) | TP53HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006083303-A1 | POLYMERIZATION PROCESS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| WO-2006009942-A1 | POLYMERIZATION PROCESS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-01-26 | — | — | WO | disclosed |
| WO-2006009945-A1 | IMPACT COPOLYMERS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-01-26 | — | — | WO | disclosed |
| WO-2006002132-A2 | OLEFIN POLYMERIZATION PROCESS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-01-05 | — | — | WO | disclosed |