Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791420 | 0.90 | HSD17B10 (0.52) | HSD17B10DRD3KDM4EHPGDTSHR | |
| SCHEMBL5790169 | 0.89 | HTT (0.56) | HSD17B10DRD3KDM4EHPGDTSHR | |
| SCHEMBL14773889 | 0.82 | DRD3 (0.47) | HSD17B10DRD3L3MBTL1BACE1SCD | |
| SCHEMBL4571036 | 0.82 | HSD17B10 (0.71) | HSD17B10KDM4EHPGDTSHRL3MBTL1 | |
| SCHEMBL30464743 | 0.82 | HSD17B10 (0.71) | HSD17B10KDM4EHPGDTSHRL3MBTL1 | |
| SCHEMBL2870268 | 0.82 | L3MBTL1 (0.53) | DRD3TSHRL3MBTL1CYP3A4MEN1 | |
| Hydrochloric Acid SCHEMBL5598108 | 0.82 | HSD17B10 (0.55) | HSD17B10KDM4EHPGDTSHRL3MBTL1 | |
| SCHEMBL17138644 | 0.82 | HSD17B10 (0.55) | HSD17B10KDM4EHPGDTSHRL3MBTL1 | |
| SCHEMBL1520714 | 0.82 | HSD17B10 (0.55) | HSD17B10KDM4EHPGDTSHRL3MBTL1 | |
| SCHEMBL893345 | 0.82 | HSD17B10 (0.60) | HSD17B10KDM4EHPGDTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012683-A1 | CHEMICAL PROCESSES AND COMPOUNDS DERIVED THEREFROM | MONASH UNIVERSITY (AU) | 2006-02-09 | — | — | WO | claimed |
| WO-2006012683-A1 | CHEMICAL PROCESSES AND COMPOUNDS DERIVED THEREFROM | MONASH UNIVERSITY (AU) | 2006-02-09 | — | — | WO | disclosed |