Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19495506 | 0.93 | HSD17B10 (0.53) | HSD17B10HDAC8HPGDKDM4ETSHR | |
| SCHEMBL23220940 | 0.85 | HSD17B10 (0.44) | HSD17B10HDAC8HPGDKDM4EGAA | |
| Fluoride SCHEMBL28344212 | 0.84 | HSD17B10 (0.51) | HSD17B10HDAC8HPGDKDM4ETSHR | |
| SCHEMBL20257645 | 0.83 | ABCB1 (0.50) | HSD17B10HDAC8HPGDKDM4ETSHR | |
| SCHEMBL27907603 | 0.83 | ABCB1 (0.54) | KDM4ETSHRGAAGRM2ABCB1 | |
| Fluoride SCHEMBL8673411 | 0.83 | HSD17B10 (0.50) | HSD17B10HDAC8HPGDKDM4ETSHR | |
| SCHEMBL5790165 | 0.82 | HSD17B10 (0.57) | HSD17B10HPGDKDM4ETSHRBACE1 | |
| Fluoride SCHEMBL5604279 | 0.81 | HSD17B10 (0.49) | HSD17B10HDAC8HPGDKDM4ETSHR | |
| SCHEMBL29437254 | 0.81 | CRHR1 (0.54) | KDM4EALDH1A1 | |
| SCHEMBL27907655 | 0.81 | ABCB1 (0.59) | HDAC8KDM4EGRM2ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190225889-A1 | METHOD TO EXTRACT BITUMEN FROM OIL SANDS USING AROMATIC AMINES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-07-25 | — | — | US | claimed |
| WO-2018111342-A1 | AMINE COMPOSITION FOR STEAM EXTRACTION OF BITUMEN | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-06-21 | — | — | WO | claimed |
| WO-2018017221-A1 | METHOD TO EXTRACT BITUMEN FROM OIL SANDS USING AROMATIC AMINES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-01-25 | — | — | WO | claimed |
| US-9090736-B2 | Rheological agent for radiation-curable coating compositions | BASF SE (DE) | 2015-07-28 | — | — | US | claimed |
| EP-2678364-B1 | RHEOLOGICAL AGENT FOR RADIATION-CURABLE COATING MATERIALS | BASF SE (DE) | 2015-04-08 | — | — | EP | claimed |
| WO-2012113739-A1 | RHEOLOGICAL AGENT FOR RADIATION-CURABLE COATING MATERIALS | BASF SE (DE) | 2012-08-30 | — | — | WO | claimed |
| US-20120214894-A1 | RHEOLOGICAL AGENT FOR RADIATION-CURABLE COATING COMPOSITIONS | BASF SE (DE) | 2012-08-23 | — | — | US | claimed |
| US-4357342-A | 1-Azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylic acid | MERCK & CO., INC. (US) | 1982-11-02 | — | — | US | claimed |
| EP-4682141-A1 | TRICYCLIC COMPOUND | ONO Pharmaceutical Co., Ltd. (JP) | 2026-01-21 | — | — | EP | disclosed |
| US-20250188023-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-06-12 | — | — | US | disclosed |
| US-12258308-B2 | Benzene derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-03-25 | — | — | US | disclosed |
| CN-119118850-A | Method for preparing amino phenethyl alcohol compound by reforming indole compound structure | 中国科学院兰州化学物理研究所 | 2024-12-13 | — | — | CN | disclosed |
| US-20240327342-A1 | COMPOUNDS HAVING S1P5 RECEPTOR AGONISTIC ACTIVITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-10-03 | — | — | US | disclosed |
| EP-4431157-A2 | 1-[[(3S)-3-METHYL-6-(4(4,4-TRIFLUOROBUTOXY)-3,4-DIHYDRONAPHTHALEN-2YL]METHYL]AZETIDINE-3-CARBOXYLIC ACID HAVING S1P5 RECEPTOR AGONIST ACTIVITY FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS AND CANCER | ONO Pharmaceutical Co., Ltd. (JP) | 2024-09-18 | — | — | EP | disclosed |
| US-4424230-A | CARBAPENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1984-01-03 | — | — | US | disclosed |
| EP-0071395-A1 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1983-02-09 | — | — | EP | disclosed |
| US-4369187-A | AMINO ACID DERIVATIVE ANTIBIOTICS | MERCK & CO., INC. (US) | 1983-01-18 | — | — | US | disclosed |
| US-4357342-A | 1-Azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylic acid | MERCK & CO., INC. (US) | 1982-11-02 | — | — | US | disclosed |
| EP-0055062-A1 | Compounds containing beta-lactams | BEECHAM GROUP PLC (GB) | 1982-06-30 | — | — | EP | disclosed |
| US-4310538-A | BACTERICIDES | MERCK & CO., INC. (US) | 1982-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12258308-B2 | Benzene derivative | PMP22, TMBIM6, MYT1 | HSD17B10 3696/4885HDAC8 2892/4885HPGD 1684/4885 |
| US-20240327342-A1 | COMPOUNDS HAVING S1P5 RECEPTOR AGONISTIC ACTIVITY | S1PR5, S1PR1, S1PR4 | HSD17B10 2211/4885HDAC8 2079/4885HPGD 2591/4885 |
| US-20250188023-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | HSD17B10 3766/4885HDAC8 2796/4885HPGD 1732/4885 |
| US-20120214894-A1 | RHEOLOGICAL AGENT FOR RADIATION-CURABLE COATING COMPOSITIONS | RAD51, XRCC6, XRCC5 | HSD17B10 4576/4885HDAC8 851/4885HPGD 2770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.