Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790185 | 1.00 | RORC (0.47) | RORCGPR119NAMPTUSP30TSHR | |
| SCHEMBL30833571 | 1.00 | RORC (0.47) | RORCGPR119NAMPTUSP30TSHR | |
| SCHEMBL27188031 | 0.92 | GPR119 (0.48) | RORCGPR119USP30 | |
| SCHEMBL3368376 | 0.88 | RORC (0.51) | RORCGPR119NAMPTUSP30 | |
| SCHEMBL3368381 | 0.88 | RORC (0.51) | RORCGPR119NAMPTUSP30 | |
| SCHEMBL3368383 | 0.88 | RORC (0.51) | RORCGPR119NAMPTUSP30 | |
| SCHEMBL26921404 | 0.87 | RORC (0.39) | RORCGPR119NAMPTUSP30TSHR | |
| SCHEMBL26921420 | 0.84 | GPR119 (0.41) | RORCGPR119USP30 | |
| SCHEMBL5790196 | 0.84 | NAMPT (0.40) | RORCGPR119NAMPTUSP30ALOX15 | |
| SCHEMBL5764197 | 0.83 | MAPT (0.52) | RORCGPR119NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247286-A1 | Oxazolidinone antibiotics and derivatives thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2006-11-02 | — | — | US | disclosed |
| EP-1656357-A1 | OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005005399-A1 | OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2005-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247286-A1 | Oxazolidinone antibiotics and derivatives thereof | OXA1L, RORC, IL17A | RORC 2/4885GPR119 1662/4885NAMPT 3383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.