Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3234142 | 0.82 | SMN1; SMN2 (0.49) | HPGDLMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL23153279 | 0.82 | ACHE (0.39) | CYP26A1PSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL2322263 | 0.80 | SMN1; SMN2 (0.47) | HPGDLMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL11766018 | 0.79 | TP53 (0.38) | HPGDTP53TDP1LMNAAOC3 | |
| SCHEMBL13075267 | 0.76 | ACHE (0.41) | TDP1CYP26A1PSEN1PSEN2APH1B | |
| SCHEMBL29339790 | 0.75 | AOC3 (0.41) | TP53TDP1LMNACYP26A1PSEN1 | |
| SCHEMBL13075234 | 0.75 | ACHE (0.39) | CYP26A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL14415658 | 0.74 | LMNA (0.50) | TP53TDP1LMNASMN1; SMN2MAPT | |
| SCHEMBL16955028 | 0.71 | TDP1 (0.42) | TP53TDP1PSEN1PSEN2APH1B | |
| SCHEMBL4580573 | 0.71 | CYP26A1 (0.50) | HPGDLMNACYP26A1SMN1; SMN2ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663201-A1 | A USE OF NOVEL 2-OXO-HETEROCYCLIC COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Korea Research Institute of Bioscience and Biotechnology (KR) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005004861-A1 | A USE OF NOVEL 2-OXO-HETEROCYCLIC COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2005-01-20 | — | — | WO | disclosed |