Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A1 | P53985 | 18/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5788474 | 0.90 | SLC16A1 (0.51) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL4798358 | 0.88 | SLC16A1 (0.63) | SLC16A1CYP2C9CYP3A4ABCB11THRB | |
| SCHEMBL5788817 | 0.85 | SLC16A1 (0.49) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL5788605 | 0.83 | SLC16A1 (0.49) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL5788548 | 0.82 | SLC16A1 (0.49) | SLC16A1CYP2C9CYP3A4ABCB11SMN1; SMN2 | |
| SCHEMBL3833122 | 0.82 | SLC16A1 (0.53) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL4803574 | 0.81 | SLC16A1 (0.54) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL5790001 | 0.80 | SLC16A1 (0.70) | SLC16A1CYP2C9CYP3A4 | |
| SCHEMBL5790956 | 0.79 | SLC16A1 (0.46) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL5786758 | 0.78 | SLC16A1 (0.66) | SLC16A1CYP2C9CYP3A4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412362-B1 | THIENO¬2,3-d|PYRIMIDINEDIONES AS INHIBITORS OF T-CELLS PROLIFERATION | ASTRAZENECA AB (SE) | 2006-08-02 | — | — | EP | claimed |