Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5789138 | 0.89 | SLC18A3 (0.52) | MGLLKMT2AMEN1POLBLMNA | |
| SCHEMBL6007347 | 0.81 | MGLL (0.59) | MGLLKMT2AMEN1POLBLMNA | |
| SCHEMBL5789497 | 0.77 | HTR2A (0.54) | MGLLKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5790034 | 0.76 | KCNH2 (0.52) | MGLLSMN1; SMN2TSHRALDH1A1HSD11B1 | |
| SCHEMBL21625275 | 0.75 | MGLL (1.00) | MGLLKMT2AMEN1POLBLMNA | |
| SCHEMBL5791361 | 0.74 | MEN1 (0.57) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL21926373 | 0.72 | KMT2A (0.74) | KMT2AMEN1SMN1; SMN2SLC18A3ALDH1A1 | |
| SCHEMBL21928858 | 0.72 | KMT2A (0.74) | KMT2AMEN1SMN1; SMN2SLC18A3ALDH1A1 | |
| SCHEMBL6007922 | 0.70 | SLC18A3 (0.57) | KMT2AMEN1POLBLMNASMN1; SMN2 | |
| SCHEMBL11103861 | 0.70 | POLB (0.73) | MGLLKMT2AMEN1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | disclosed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | disclosed |