Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007347 | 0.89 | MGLL (0.59) | SLC18A3LMNATSHRSMN1; SMN2POLB | |
| SCHEMBL6007356 | 0.89 | HTR2A (0.61) | LMNAKMT2AMEN1HTR2AKCNH2 | |
| SCHEMBL3838692 | 0.85 | HTR2A (0.61) | SLC18A3LMNASMN1; SMN2HTR2A | |
| SCHEMBL6009245 | 0.85 | MGLL (0.54) | LMNAKMT2AMEN1HTR2AKCNH2 | |
| SCHEMBL3838687 | 0.85 | HTR2A (0.61) | SLC18A3LMNASMN1; SMN2HTR2A | |
| SCHEMBL3838690 | 0.85 | HTR2A (0.61) | SLC18A3LMNASMN1; SMN2HTR2A | |
| SCHEMBL6007451 | 0.85 | MEN1 (0.57) | KMT2AMEN1HTR2AKCNH2 | |
| SCHEMBL30516673 | 0.83 | SLC18A3 (0.74) | SLC18A3LMNATSHRSMN1; SMN2POLB | |
| SCHEMBL6007909 | 0.81 | MGLL (0.54) | KMT2AMEN1HTR2AKCNH2 | |
| SCHEMBL10340077 | 0.81 | HTR2A (0.76) | SLC18A3HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | claimed |
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | disclosed |