Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A1 | P53985 | 15/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.36 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.36 |
| ▸ | SLC16A7 | O60669 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4796733 | 0.89 | SLC16A1 (0.51) | SLC16A1CYP2C9CYP3A4ALDH1A1MEN1 | |
| SCHEMBL4796688 | 0.79 | SLC16A1 (0.62) | SLC16A1CYP2C9CYP3A4ALDH1A1MEN1 | |
| SCHEMBL5788548 | 0.78 | SLC16A1 (0.49) | SLC16A1CYP2C9CYP3A4MEN1KMT2A | |
| SCHEMBL5788474 | 0.77 | SLC16A1 (0.51) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL5788605 | 0.75 | SLC16A1 (0.49) | SLC16A1CYP2C9CYP3A4ABCB11MAPKAPK2 | |
| SCHEMBL5787264 | 0.74 | SLC16A1 (0.47) | SLC16A1CYP2C9CYP3A4ABCB11MAPKAPK2 | |
| SCHEMBL5790563 | 0.74 | SLC16A1 (0.48) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL5791636 | 0.74 | SLC16A1 (0.63) | SLC16A1CYP2C9CYP3A4ABCB11MAPKAPK2 | |
| SCHEMBL3833746 | 0.73 | SLC16A1 (0.61) | SLC16A1CYP2C9CYP3A4ALDH1A1MEN1 | |
| SCHEMBL5788817 | 0.73 | SLC16A1 (0.49) | SLC16A1CYP2C9CYP3A4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412362-B1 | THIENO¬2,3-d|PYRIMIDINEDIONES AS INHIBITORS OF T-CELLS PROLIFERATION | ASTRAZENECA AB (SE) | 2006-08-02 | — | — | EP | claimed |