Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3964892 | 1.00 | EPHX1 (0.41) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL29598901 | 0.98 | EPHX1 (0.38) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL17651116 | 0.80 | EPHX1 (0.40) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL11605920 | 0.80 | EPHX1 (0.40) | EPHX1ALDH1A1SMN1; SMN2NPC1CYP3A4 | |
| SCHEMBL7696325 | 0.80 | EPHX1 (0.40) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL11805037 | 0.78 | CES2 (0.41) | EPHX1ALDH1A1SMN1; SMN2NPC1HTT | |
| SCHEMBL6860576 | 0.77 | EPHX1 (0.37) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL6544816 | 0.77 | EPHX1 (0.38) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL5716953 | 0.77 | EPHX1 (0.38) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL5716958 | 0.77 | EPHX1 (0.38) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006015885-A1 | AMINO ACID DEHYDROGENASE-DERIVED BIOCATALYSTS | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2006-02-16 | — | — | WO | disclosed |