Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 3/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13025340 | 0.94 | SMN1; SMN2 (0.40) | KMT2ABTKMAPTTRPC6KYAT3 | |
| SCHEMBL2867281 | 0.92 | GAA (0.37) | GAAKMT2ABTKFGFR1BRD4 | |
| SCHEMBL2861463 | 0.89 | PDE2A (0.35) | BTKFGFR1KYAT3AADATPDE2A | |
| SCHEMBL2867315 | 0.89 | PDGFRB (0.33) | GAABTKFGFR1TRPC6KYAT3 | |
| SCHEMBL2869051 | 0.88 | TSHR (0.34) | BTKFGFR1TRPC6LMNAKYAT3 | |
| SCHEMBL2857657 | 0.88 | POLB (0.37) | KMT2ABTKFGFR1TRPC6KYAT3 | |
| SCHEMBL2861219 | 0.87 | KYAT3 (0.36) | GAAKMT2ABTKFGFR1KYAT3 | |
| SCHEMBL13025396 | 0.86 | SMN1; SMN2 (0.40) | KMT2ABTKMAPTEGFRMMP13 | |
| SCHEMBL2868573 | 0.86 | ADORA3 (0.39) | KMT2ABTKFGFR1MAPTKYAT3 | |
| SCHEMBL2868584 | 0.85 | KMT2A (0.37) | GAAKMT2AFGFR1PDE2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719771-A1 | PYRAZOLOQUINOLONE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2006-11-08 | — | — | EP | disclosed |