Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790391 | 0.91 | HTT (0.46) | MGLLMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5789503 | 0.86 | MEN1 (0.48) | MGLLMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5789441 | 0.86 | MAPK14 (0.50) | MGLLMEN1KMT2AALDH1A1HTT | |
| SCHEMBL5789394 | 0.84 | MEN1 (0.46) | MGLLMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5789577 | 0.83 | POLB (0.45) | MGLLMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5789432 | 0.83 | CA1 (0.46) | MGLLMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5790876 | 0.83 | MGLL (0.47) | MGLLMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5792534 | 0.81 | MEN1 (0.48) | MGLLMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5789654 | 0.81 | CA1 (0.44) | MGLLMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5789479 | 0.81 | GAA (0.46) | MGLLMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006016237-A2 | HETEROCYCLIC DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-16 | — | — | WO | disclosed |