SCHEMBL5791560

SCHEMBL5791560

NC(=O)C1=CC=CNC=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28296127 0.77 NPSR1 (0.34)
SCHEMBL27617110 0.68 ADORA3 (0.30)
SCHEMBL8396507 0.68
SCHEMBL29638783 0.68
SCHEMBL1868811 0.67
SCHEMBL22747796 0.64 SLC22A6 (0.30)
SCHEMBL28485690 0.64
SCHEMBL29768627 0.64
SCHEMBL29440550 0.64
SCHEMBL7854382 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112513049-B Heterocyclic compounds and their use in the prevention or treatment of bacterial infections 拜欧蒂姆公司 2023-11-28 CN disclosed
CN-116635378-A Bicyclic 1, 4-diazacycloheptanones and therapeutic uses thereof 赛特凯恩蒂克公司 2023-08-22 CN disclosed
CN-112513049-A Heterocyclic compounds and their use in the prevention or treatment of bacterial infections 拜欧蒂姆公司 2021-03-16 CN disclosed
WO-2005089515-A9 METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES BRIGHAM & WOMENS HOSPITAL (US) 2006-01-26 WO disclosed