Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | AGER | Q15109 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL15167306 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL21230286 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL5610319 | 0.82 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL936114 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL3538383 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| Benzene SCHEMBL1202117 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL22031727 | 0.79 | KDM4E (0.52) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL7194177 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL1202477 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL3963715 | 0.78 | P2RX7 (0.48) | KDM4EALDH1A1MAPTL3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505966-A4 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2006-08-30 | — | — | EP | disclosed |
| EP-1505966-A1 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003099276-A1 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |
| EP-0329606-A2 | Antibiotics from myxocuccos | CIBA-GEIGY AG (CH) | 1989-08-23 | — | — | EP | disclosed |