Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19207558 | 0.81 | HDAC4 (0.39) | — | |
| SCHEMBL3408485 | 0.75 | SLC6A4 (0.47) | — | |
| SCHEMBL3408732 | 0.75 | SLC6A4 (0.51) | — | |
| SCHEMBL16516607 | 0.74 | HDAC4 (0.40) | — | |
| SCHEMBL3413223 | 0.74 | SLC6A4 (0.54) | — | |
| SCHEMBL6259078 | 0.71 | SLC6A3 (0.40) | GSK3B | |
| SCHEMBL4283467 | 0.68 | SLC6A4 (0.55) | — | |
| SCHEMBL7366122 | 0.68 | SLC6A4 (0.55) | — | |
| SCHEMBL7047850 | 0.68 | SLC6A4 (0.51) | — | |
| SCHEMBL7388 | 0.67 | OPRM1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505966-A4 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2006-08-30 | — | — | EP | disclosed |
| EP-1505966-A1 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003099276-A1 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |