Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 4/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 6/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792856 | 0.89 | SLC1A3 (0.44) | IDO1TACR1KIF11KMT2ASLC1A3 | |
| SCHEMBL5790217 | 0.88 | TACR1 (0.57) | IDO1TACR1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL5790287 | 0.88 | SLC6A4 (0.44) | IDO1TACR1KIF11KMT2ASLC1A3 | |
| SCHEMBL5790686 | 0.87 | IDO1 (0.51) | IDO1TACR1MAOBSLC1A3SLC1A2 | |
| SCHEMBL5793858 | 0.85 | CHRNB2 (0.47) | IDO1KIF11KMT2APPARG | |
| SCHEMBL5791679 | 0.85 | CHRM3 (0.39) | IDO1TACR1KIF11KMT2ASLC1A3 | |
| SCHEMBL5790390 | 0.84 | TACR1 (0.50) | IDO1TACR1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL5792861 | 0.82 | TACR1 (0.48) | IDO1TACR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5793395 | 0.81 | TACR1 (0.49) | IDO1TACR1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL5792223 | 0.81 | TACR1 (0.49) | IDO1TACR1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006014942-A1 | ARYLOXYALKYLAMINE NK-1/SSRI INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-02-09 | — | — | WO | claimed |