Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790217 | 0.91 | TACR1 (0.57) | IDO1HTR2AHTR2CHTR2BTACR1 | |
| SCHEMBL5790375 | 0.87 | IDO1 (0.44) | IDO1MAOBNR4A2SLC1A1FFAR1 | |
| SCHEMBL5791685 | 0.87 | IDO1 (0.44) | IDO1TACR1MAOBSLC1A3SLC1A2 | |
| SCHEMBL5790390 | 0.86 | TACR1 (0.50) | IDO1HTR2AHTR2CHTR2BTACR1 | |
| SCHEMBL5792856 | 0.86 | SLC1A3 (0.44) | IDO1TACR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5790274 | 0.86 | IDO1 (0.45) | IDO1TACR1MAOBSLC1A5TAAR1 | |
| SCHEMBL5792475 | 0.85 | CETP (0.43) | TACR1EPHX1 | |
| SCHEMBL5793923 | 0.85 | IDO1 (0.44) | IDO1MAOBTAAR1FFAR1FFAR4 | |
| SCHEMBL5790213 | 0.85 | PKM (0.48) | IDO1TACR1MAOBSLC1A5FFAR1 | |
| SCHEMBL5791244 | 0.84 | IDO1 (0.48) | IDO1MAOBSLC1A5TAAR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006014942-A1 | ARYLOXYALKYLAMINE NK-1/SSRI INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-02-09 | — | — | WO | claimed |