Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 5/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266097 | 0.90 | SMN1; SMN2 (0.48) | MEN1KMT2AGFERMAPTALDH1A1 | |
| SCHEMBL266705 | 0.75 | ACHE (0.43) | GFERMAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL267335 | 0.74 | SMN1; SMN2 (0.43) | MEN1KMT2AGFERMAPTALDH1A1 | |
| SCHEMBL268502 | 0.73 | AKR1C4 (0.65) | MEN1KMT2AGFERAKR1C2AKR1C1 | |
| SCHEMBL28997861 | 0.71 | MEN1 (0.69) | MEN1KMT2AMAPTALDH1A1ABL1 | |
| SCHEMBL268374 | 0.71 | ALDH1A1 (0.55) | MEN1KMT2AAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL11867128 | 0.70 | KMT2A (0.54) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL13137734 | 0.70 | MEN1 (0.62) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL267931 | 0.70 | HPGD (0.57) | MEN1KMT2AGFERAKR1C2AKR1C1 | |
| SCHEMBL14075207 | 0.70 | AKR1C2 (0.69) | MEN1KMT2AGFERAKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1614676-A1 | COMPOUND INHIBITING IN VIVO PHOSPHORUS TRANSPORT AND MEDICINE CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-01-11 | — | — | EP | disclosed |