Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 6/20 | 0.41 |
| ▸ | GHSR | Q92847 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819554 | 0.89 | FEN1 (0.50) | CYP2D6FEN1BRD4GHSRKCNH2 | |
| SCHEMBL21033691 | 0.89 | FEN1 (0.50) | CYP2D6FEN1BRD4GHSRKCNH2 | |
| SCHEMBL5793560 | 0.89 | CYP2D6 (0.56) | CYP2D6BRD4CACNA2D1GHSRKCNH2 | |
| SCHEMBL5793556 | 0.89 | CYP2D6 (0.56) | CYP2D6BRD4CACNA2D1GHSRKCNH2 | |
| SCHEMBL5792111 | 0.89 | CYP2D6 (0.56) | CYP2D6BRD4CACNA2D1GHSRKCNH2 | |
| SCHEMBL5791736 | 0.87 | FEN1 (0.49) | FEN1BRD4CHEK2FPR3FPR2 | |
| SCHEMBL5794303 | 0.86 | CYP2D6 (0.72) | CYP2D6FEN1GHSRKCNH2CHEK2 | |
| SCHEMBL20528749 | 0.85 | GHSR (0.55) | CYP2D6FEN1BRD4GHSRKCNH2 | |
| SCHEMBL5792037 | 0.85 | GHSR (0.55) | CYP2D6FEN1BRD4GHSRKCNH2 | |
| SCHEMBL21632618 | 0.84 | GHSR (0.50) | CYP2D6FEN1BRD4GHSRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |