Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 10/20 | 0.45 |
| ▸ | GHSR | Q92847 | 4/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793560 | 1.00 | CYP2D6 (0.56) | CYP2D6BRD4CACNA2D1GHSROPRM1 | |
| SCHEMBL5792111 | 1.00 | CYP2D6 (0.56) | CYP2D6BRD4CACNA2D1GHSROPRM1 | |
| SCHEMBL5794692 | 0.90 | CYP2D6 (0.57) | CYP2D6BRD4GHSRKCNH2CYP3A4 | |
| SCHEMBL5794688 | 0.90 | CYP2D6 (0.57) | CYP2D6BRD4GHSRKCNH2CYP3A4 | |
| SCHEMBL5792392 | 0.89 | CYP2D6 (0.51) | CYP2D6BRD4CACNA2D1GHSROPRM1 | |
| SCHEMBL5815296 | 0.87 | GHSR (0.53) | CYP2D6BRD4GHSRKCNH2 | |
| SCHEMBL5815290 | 0.87 | GHSR (0.53) | CYP2D6BRD4GHSRKCNH2 | |
| SCHEMBL5791009 | 0.87 | CYP2D6 (0.74) | CYP2D6CACNA2D1GHSRKCNH2CYP3A4 | |
| SCHEMBL5794299 | 0.86 | CYP2D6 (0.57) | CYP2D6CACNA2D1GHSROPRM1KCNH2 | |
| SCHEMBL5792506 | 0.86 | BRD4 (0.47) | CYP2D6BRD4CACNA2D1GHSROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |