Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL944969 | 0.83 | MAPT (1.00) | MAPTALDH1A1CHRM1KDM4EHSD17B10 | |
| SCHEMBL27887747 | 0.82 | MAPT (0.74) | MAPTALDH1A1CHRM1KDM4EHSD17B10 | |
| SCHEMBL28352297 | 0.81 | MAPT (0.72) | MAPTALDH1A1CHRM1KDM4EHSD17B10 | |
| SCHEMBL20561440 | 0.80 | MAPT (0.75) | MAPTALDH1A1CHRM1KDM4EHSD17B10 | |
| SCHEMBL5413290 | 0.77 | MAPT (0.67) | MAPTALDH1A1CHRM1KDM4EHSD17B10 | |
| Procodazole SCHEMBL349966 | 0.76 | CHRM1 (1.00) | MAPTALDH1A1CHRM1KDM4ECYP1A2 | |
| Procodazole SCHEMBL838841 | 0.76 | CHRM1 (1.00) | MAPTALDH1A1CHRM1KDM4ECYP1A2 | |
| Procodazole SCHEMBL29404024 | 0.76 | CHRM1 (1.00) | MAPTALDH1A1CHRM1KDM4ECYP1A2 | |
| SCHEMBL25475139 | 0.75 | ALDH1A1 (0.65) | MAPTALDH1A1CHRM1KDM4EHSD17B10 | |
| SCHEMBL19368796 | 0.75 | CHRM1 (0.74) | MAPTALDH1A1CHRM1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012277-A2 | BIOCATALYTIC PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED PRAMIPEXOLE | AMR TECHNOLOGY, INC. (US) | 2006-02-02 | — | — | WO | disclosed |