Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 15/20 | 0.61 |
| ▸ | PPARA | Q07869 | 12/20 | 0.57 |
| ▸ | PPARD | Q03181 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080934 | 0.87 | ALDH1A1 (0.57) | ALDH1A1MAPK1L3MBTL1PPARGPPARA | |
| SCHEMBL5795465 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1PPARGPPARA | |
| SCHEMBL6784181 | 0.82 | ALDH1A1 (0.96) | ALDH1A1MAPK1L3MBTL1KMT2ALIPE | |
| SCHEMBL1171464 | 0.81 | ALDH1A1 (0.74) | ALDH1A1MAPK1L3MBTL1PPARGPPARA | |
| SCHEMBL5795674 | 0.81 | PPARG (0.83) | PPARGPPARAPPARD | |
| SCHEMBL11684699 | 0.81 | ALDH1A1 (0.74) | ALDH1A1MAPK1L3MBTL1PPARGPPARA | |
| SCHEMBL11566625 | 0.81 | PPARG (0.70) | PPARGPPARAPPARDMEN1CYP1A2 | |
| SCHEMBL5793165 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1PPARGPPARA | |
| SCHEMBL361779 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL5795000 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006035157-A2 | SUBSTITUTED N-(BENZYL)PHENYLACETAMIDE DERIVATIVE COMPOUNDS, PREPARATION METHOD THEREOF AND USES OF SAME AS PPAR LIGANDS IN THE TREATMENT OF LIPID AND/OR GLUCIDIC DISORDERS | GENFIT (FR) | 2006-04-06 | — | — | WO | disclosed |