Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 12/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 4/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081371 | 0.88 | PPARA (0.61) | ALDH1A1MAPK1L3MBTL1PPARGPPARA | |
| SCHEMBL5793096 | 0.86 | ALDH1A1 (0.64) | ALDH1A1MAPK1L3MBTL1PPARGPPARA | |
| SCHEMBL6542904 | 0.84 | PPARG (0.53) | PPARGPPARAPPARDCYP4F2CYP4A11 | |
| SCHEMBL5795203 | 0.83 | PPARG (0.64) | PPARGPPARAPPARDCYP4F2CYP4A11 | |
| SCHEMBL21336442 | 0.82 | L3MBTL1 (0.65) | ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11215916 | 0.81 | PPARG (0.61) | PPARGPPARAPPARDCYP4F2CYP4A11 | |
| SCHEMBL7248386 | 0.81 | PPARG (0.61) | PPARGPPARAPPARDCYP4F2CYP4A11 | |
| SCHEMBL5793165 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1PPARGPPARA | |
| SCHEMBL1137350 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MAPK1L3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL5795000 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006035157-A2 | SUBSTITUTED N-(BENZYL)PHENYLACETAMIDE DERIVATIVE COMPOUNDS, PREPARATION METHOD THEREOF AND USES OF SAME AS PPAR LIGANDS IN THE TREATMENT OF LIPID AND/OR GLUCIDIC DISORDERS | GENFIT (FR) | 2006-04-06 | — | — | WO | disclosed |