SCHEMBL5793262

SCHEMBL5793262

CCCCOC(OCCCC)(OCCCC)N(c1nc(N)nc(N)n1)C(OC)(OC)OC

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.34
PKM P14618 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CDK1 P06493 1/20 0.32
CCNB1 P14635 1/20 0.32
CCNA2 P20248 1/20 0.32
CDK2 P24941 1/20 0.32
CCNA1 P78396 1/20 0.32
PIN1 Q13526 1/20 0.32
HRH2 P25021 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
HTT P42858 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MCHR1 Q99705 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8356312 0.71 LMNA (0.32) LMNAPKMSMN1; SMN2
SCHEMBL16423542 0.70 CDK1 (0.38) LMNAPKMSMN1; SMN2CDK1CCNB1
SCHEMBL7108634 0.69 MAPT (0.32) LMNAPKMSMN1; SMN2
SCHEMBL1012240 0.69 CDK1 (0.31) LMNACDK1CCNB1CCNA2CDK2
SCHEMBL8214121 0.68 TLR8 (0.42) LMNAPKMSMN1; SMN2CDK1CCNB1
SCHEMBL8934295 0.68 LMNA (0.37) LMNAPKMSMN1; SMN2CDK1CCNB1
SCHEMBL8719022 0.67 LMNA (0.41) LMNAPKMSMN1; SMN2CDK1CCNB1
Methoxymethane SCHEMBL6774591 0.67 TSHR (0.44) LMNAPKMCDK1CCNB1CCNA2
SCHEMBL4452232 0.67 CDK1 (0.32) LMNACDK1CCNB1CCNA2CDK2
SCHEMBL9769720 0.66 TSHR (0.48) LMNAPKMCDK1CCNB1CCNA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006014708-A9 THERMALLY SENSITIVE COATING COMPOSITIONS USEFUL FOR LITHOGRAPHIC ELEMENTS CITIPLATE INC (US) 2006-04-06 WO disclosed
WO-2006014708-A2 THERMALLY SENSITIVE COATING COMPOSITIONS USEFUL FOR LITHOGRAPHIC ELEMENTS CITIPLATE, INC. (US) 2006-02-09 WO disclosed
US-20060019194-A1 Thermally sensitive coating compositions useful for lithographic elements CITIPLATE, INC. 2006-01-26 US disclosed
US-20030008229-A1 A mixture of(a) a novolak resin, (b) a crosslinking agent for novolak resin comprising a melamine derivative, (c) a thermochemical acid generating compound, (d) a polymeric dissolution inhibitor and an infrared radiation absorber CITIPLATE, INC. 2003-01-09 US disclosed
WO-2003001301-A1 THERMALLY SENSITIVE COATING COMPOSITIONS USEFUL FOR LITHOGRAPHIC ELEMENTS CITIPLATE, INC. (US) 2003-01-03 WO disclosed
EP-0245700-B1 Alkylcarbamylmethylated aminotriazine crosslinking agents and curable compositions containing the same AMERICAN CYANAMID CO (US) 1994-08-24 EP disclosed
EP-0306471-B1 BLOCKED ACID CATALYSTS Monsanto Company (US) 1992-08-26 EP disclosed
US-5089561-A Alkylcarbamylmethylated aminotriazine crosslinking agents and curable compositions containing the same AMERICAN CYANAMID COMPANY (US) 1992-02-18 US disclosed
US-5006653-A Oligomers; coatings resistant to detergent, brines, wear; fillers for binders, molds, insulation AMERICAN CYANAMID COMPANY (US) 1991-04-09 US disclosed
US-4839427-A GLYCIDAMIDE-BLOCKED SULFONIC ACIDS; AMINO RESIN CURING AGENTS; SOLVENT COATINGS; POT LIFE MONSANTO COMPANY (US) 1989-06-13 US disclosed
US-4835227-A BLOCKING SULFONIC ACIDS WITH GLYCIDAMIDES MONSANTO COMPANY (US) 1989-05-30 US disclosed
EP-0306472-A2 Resin systems cured with blocked acid catalysts MONSANTO COMPANY (US) 1989-03-08 EP disclosed
EP-0306471-A2 Blocked acid catalysts Monsanto Company (US) 1989-03-08 EP disclosed
US-4710542-A PROTECTIVE COATINGS HAVING EXCELLENT RESISTANCE TO DETERGENTS AND BRINES AMERICAN CYANAMID COMPANY (US) 1987-12-01 US disclosed
EP-0245700-A2 Alkylcarbamylmethylated aminotriazine crosslinking agents and curable compositions containing the same CYTEC TECHNOLOGY CORP. (US) 1987-11-19 EP disclosed
US-4540649-A Water developable photopolymerizable composition and printing plate element containing same NAPP SYSTEMS (USA) INC. (US) 1985-09-10 US disclosed