SCHEMBL1012240

SCHEMBL1012240

CCCCOC(O)(Nc1nc(N)nc(N)n1)OC

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
CCNA2 P20248 1/20 0.31
CDK2 P24941 1/20 0.31
CCNA1 P78396 1/20 0.31
PIN1 Q13526 1/20 0.31
TLR8 Q9NR97 5/20 0.31
TLR7 Q9NYK1 5/20 0.31
HRH2 P25021 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4452232 0.81 CDK1 (0.32) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL5157470 0.80 CDK1 (0.38) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL16423542 0.76 CDK1 (0.38) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL16423545 0.73 CDK1 (0.34) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL36243 0.71 CDK1 (0.33) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL5804830 0.70 HSD17B10 (0.36) LMNAHSD17B10
SCHEMBL8854656 0.69 HSD17B10 (0.35) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL5848944 0.69
SCHEMBL5793262 0.69 LMNA (0.34) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL5792612 0.68 CDK1 (0.32) CDK1CCNB1CCNA2CDK2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58215466-A None JP disclosed
EP-1482014-B1 Coating film formation process and coated article HONDA MOTOR CO LTD (JP) 2011-01-05 EP disclosed
US-20040241450-A1 Coating film formation process and coated article HONDA MOTOR CO., LTD. 2004-12-02 US disclosed
EP-1482014-A1 Coating film formation process and coated article HONDA MOTOR CO., Ltd. (JP) 2004-12-01 EP disclosed
EP-0973834-A1 POWDER COATING COMPOSITION CONTAINING LAMELLAR PIGMENT AND RESIN ENGELHARD CORPORATION (US) 2000-01-26 EP disclosed
WO-1998046682-A1 POWDER COATING COMPOSITION CONTAINING LAMELLAR PIGMENT AND RESIN ENGELHARD CORPORATION (US) 1998-10-22 WO disclosed
US-5824144-A Powder coating composition and method ENGELHARD CORPORATION (US) 1998-10-20 US disclosed
EP-0601378-B1 Mica-containing pigment composition NIPPON PAINT CO LTD (JP) 1997-04-16 EP disclosed
EP-0684291-A1 Mica group pigment-containing water-based coating composition Nippon Paint Co., Ltd. (JP) 1995-11-29 EP disclosed
US-5378275-A Melamine resin, glossy steel finish, automobiles NIPPON PAINT CO., LTD. (JP) 1995-01-03 US disclosed
EP-0601378-A1 Mica-containing pigment composition Nippon Paint Co., Ltd. (JP) 1994-06-15 EP disclosed
JP-S58215466-A MATTE ELECTRODEPOSITION COATING METHOD HONNY CHEM IND CO LTD 1983-12-14 JP disclosed