Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793540 | 1.00 | KMT2A (0.40) | KMT2ALMNASMN1; SMN2TP53CYP3A4 | |
| SCHEMBL4301033 | 0.88 | KMT2A (0.45) | KMT2ALMNASMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL14340741 | 0.82 | LMNA (0.41) | LMNASMN1; SMN2TP53ALDH1A1MAPT | |
| SCHEMBL4307213 | 0.78 | GAA (0.43) | KMT2ALMNASMN1; SMN2ALDH1A1P2RX7 | |
| SCHEMBL1141120 | 0.78 | LMNA (0.37) | KMT2ALMNASMN1; SMN2TP53CYP3A4 | |
| SCHEMBL6096675 | 0.76 | BRD4 (0.41) | KMT2ACYP3A4MAPT | |
| SCHEMBL12201463 | 0.73 | SYK (0.38) | LMNASMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL8127865 | 0.72 | LMNA (0.39) | LMNASMN1; SMN2TP53ALDH1A1MAPT | |
| SCHEMBL5818571 | 0.72 | LMNA (0.36) | KMT2ALMNASMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL2572685 | 0.72 | SMN1; SMN2 (0.43) | KMT2ALMNASMN1; SMN2TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006026760-A2 | 1-AMINO IMIDAZO-CONTAINING COMPOUNDS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-09 | — | — | WO | disclosed |