Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301033 | 0.78 | KMT2A (0.45) | LMNASMN1; SMN2ALDH1A1MAPTMAPK1 | |
| SCHEMBL6096675 | 0.75 | BRD4 (0.41) | MAPTCYP3A4KMT2A | |
| SCHEMBL5793537 | 0.72 | KMT2A (0.40) | LMNASMN1; SMN2ALDH1A1MAPTMAPK1 | |
| SCHEMBL5793540 | 0.72 | KMT2A (0.40) | LMNASMN1; SMN2ALDH1A1MAPTMAPK1 | |
| SCHEMBL12201463 | 0.71 | SYK (0.38) | LMNASMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL4307213 | 0.71 | GAA (0.43) | LMNASMN1; SMN2ALDH1A1AKT1KMT2A | |
| SCHEMBL4296286 | 0.70 | KMT2A (0.40) | LMNASMN1; SMN2ALDH1A1MAPTTDP1 | |
| SCHEMBL1654086 | 0.69 | KDM4E (0.42) | LMNASMN1; SMN2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL14340741 | 0.68 | LMNA (0.41) | LMNASMN1; SMN2ALDH1A1MAPTMAPK1 | |
| SCHEMBL5571713 | 0.68 | KDM4E (0.41) | LMNASMN1; SMN2ALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006026760-A2 | 1-AMINO IMIDAZO-CONTAINING COMPOUNDS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-09 | — | — | WO | disclosed |