Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 2/20 | 0.76 |
| ▸ | CTSG | P08311 | 8/20 | 0.67 |
| ▸ | KLK7 | P49862 | 8/20 | 0.67 |
| ▸ | KLK14 | Q9P0G3 | 8/20 | 0.67 |
| ▸ | KLK5 | Q9Y337 | 8/20 | 0.67 |
| ▸ | CTRC | Q99895 | 2/20 | 0.67 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.65 |
| ▸ | ELANE | P08246 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5921134 | 0.89 | C1R (0.68) | C1RCTSGKLK7KLK14KLK5 | |
| SCHEMBL914361 | 0.86 | C1R (0.74) | C1RCTSGKLK7KLK14KLK5 | |
| SCHEMBL5790698 | 0.86 | C1R (0.72) | C1RCTSGKLK7KLK14KLK5 | |
| SCHEMBL692226 | 0.85 | C1R (1.00) | C1RCTSGKLK7KLK14KLK5 | |
| SCHEMBL30366271 | 0.85 | C1R (1.00) | C1RCTSGKLK7KLK14KLK5 | |
| SCHEMBL5371767 | 0.83 | C1R (0.69) | C1RCTSGKLK7KLK14KLK5 | |
| SCHEMBL5794442 | 0.82 | ELANE (0.71) | C1RCTSGKLK7KLK14KLK5 | |
| SCHEMBL5387023 | 0.82 | C1R (0.66) | C1RCTSGKLK7KLK14KLK5 | |
| SCHEMBL914093 | 0.82 | C1R (0.66) | C1RCTSGKLK7KLK14KLK5 | |
| SCHEMBL914380 | 0.82 | C1R (0.70) | C1RCTSGKLK7KLK14KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |