Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.71 |
| ▸ | C1R | P00736 | 5/20 | 0.66 |
| ▸ | KLK7 | P49862 | 7/20 | 0.59 |
| ▸ | KLK14 | Q9P0G3 | 7/20 | 0.59 |
| ▸ | KLK5 | Q9Y337 | 7/20 | 0.59 |
| ▸ | CTSG | P08311 | 6/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CTRC | Q99895 | 2/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984612 | 0.83 | ELANE (1.00) | ELANEC1RKLK7KLK14KLK5 | |
| SCHEMBL5793545 | 0.82 | C1R (0.76) | ELANEC1RKLK7KLK14KLK5 | |
| SCHEMBL5790698 | 0.81 | C1R (0.72) | ELANEC1RKLK7KLK14KLK5 | |
| SCHEMBL30366271 | 0.80 | C1R (1.00) | ELANEC1RKLK7KLK14KLK5 | |
| SCHEMBL692226 | 0.80 | C1R (1.00) | ELANEC1RKLK7KLK14KLK5 | |
| SCHEMBL913690 | 0.79 | ELANE (0.74) | ELANEC1RKLK7KLK14KLK5 | |
| SCHEMBL5921767 | 0.78 | C1R (0.63) | ELANEC1RKLK7KLK14KLK5 | |
| SCHEMBL914093 | 0.77 | C1R (0.66) | ELANEC1RKLK7KLK14KLK5 | |
| SCHEMBL5387023 | 0.77 | C1R (0.66) | ELANEC1RKLK7KLK14KLK5 | |
| SCHEMBL914380 | 0.77 | C1R (0.70) | ELANEC1RKLK7KLK14KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |