Diethylamine

Diethylamine

SCHEMBL5793553

CCCCCCCCCCCCCCCCCC(=O)OCC.CCNCC

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CCKAR

The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.62
PAM P19021 2/20 0.56
TSHR P16473 2/20 0.53
MAPT P10636 1/20 0.53
CYP1A2 P05177 1/20 0.52
LMNA P02545 4/20 0.51
ALDH1A1 P00352 2/20 0.51
DNM1 Q05193 1/20 0.51
KDM4E B2RXH2 1/20 0.50
DUSP3 P51452 1/20 0.50
GAA P10253 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
PRKCA P17252 1/20 0.47
PRKCE Q02156 1/20 0.47
PRKCQ Q04759 1/20 0.47
PRKCD Q05655 1/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethylamine SCHEMBL358240 0.92 CYP1A2 (0.59) DGKAPAMTSHRCYP1A2ALDH1A1
SCHEMBL8375548 0.90 DGKA (0.75) DGKAPAMTSHRMAPTCYP1A2
SCHEMBL1645398 0.90 DGKA (0.75) DGKAPAMTSHRMAPTCYP1A2
Hexane SCHEMBL3151787 0.90 DGKA (0.75) DGKAPAMTSHRMAPTCYP1A2
SCHEMBL8322451 0.90 DGKA (0.75) DGKAPAMTSHRMAPTCYP1A2
SCHEMBL11527039 0.90 DGKA (0.75) DGKAPAMTSHRMAPTCYP1A2
Hexane SCHEMBL2349171 0.90 DGKA (0.75) DGKAPAMTSHRMAPTCYP1A2
SCHEMBL454 0.90 DGKA (0.75) DGKAPAMTSHRMAPTCYP1A2
SCHEMBL116995 0.90 DGKA (0.75) DGKAPAMTSHRMAPTCYP1A2
Hexane SCHEMBL3138126 0.90 DGKA (0.75) DGKAPAMTSHRMAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200054587-A1 METHODS AND MATERIALS FOR REDUCING SCARRING ASSOCIATED WITH ARTHROFIBROSIS OR TENDON INJURY MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2020-02-20 US disclosed
US-20200038348-A1 METHODS AND MATERIALS FOR REDUCING SCAR FORMATION DURING WOUND HEALING MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2020-02-06 US disclosed
WO-2018151838-A1 METHODS AND MATERIALS FOR REDUCING SCAR FORMATION DURING WOUND HEALING MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2018-08-23 WO disclosed
US-20180185258-A1 SKIN CARE COMPOSITIONS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2018-07-05 US disclosed
WO-2006043940-A1 TOPICAL SKIN LIGHTENING CREAM VU HUYNH ANTHONY (US) 2006-04-27 WO disclosed
US-20060083697-A1 Topical skin lightening cream HUYNH ANTHONY V 2006-04-20 US disclosed
US-20040185016-A1 Compositions for treatment of hyperpigmentation and methods for making and using such compositions STIEFEL LABORATORIES, INC. 2004-09-23 US disclosed
US-6699464-B1 HYDROQUINONE, SUNSCREENS, ANTIOXIDANTS AND EMULSIFIERS AND EMOLLIENTS; PHYSICAL AND CHEMICAL STABILITY STIEFEL LABORATORIES, INC. 2004-03-02 US disclosed