Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL5793553 | 0.92 | DGKA (0.62) | CYP1A2GAAALDH1A1KMT2AALOX15 | |
| SCHEMBL8570508 | 0.88 | CYP1A2 (0.73) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL50610 | 0.88 | CYP1A2 (0.73) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL130596 | 0.88 | CYP1A2 (0.52) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL132536 | 0.88 | CYP1A2 (0.52) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL8367259 | 0.87 | CYP1A2 (0.55) | CYP1A2GAAMGAMSIMGAM2 | |
| Dimethylamine SCHEMBL16909987 | 0.86 | CYP1A2 (0.64) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL6055406 | 0.85 | CYP1A2 (0.70) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL495925 | 0.85 | CYP1A2 (0.70) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL33870 | 0.85 | CYP1A2 (0.70) | CYP1A2GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014100921-A1 | FOAM GASKET AND BONDING TAPE BASED ON POLYURETHANE DISPERSIONS | SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) | 2014-07-03 | — | — | WO | claimed |
| US-20260005355-A1 | CURABLE POTTING MATERIAL FOR AUTOMOTIVE BATTERY PACKS | SIKA TECHNOLOGY AG (CH) | 2026-01-01 | — | — | US | disclosed |
| EP-4655329-A1 | CURABLE POTTING MATERIAL FOR AUTOMOTIVE BATTERY PACKS | Sika Technology AG (CH) | 2025-12-03 | — | — | EP | disclosed |
| EP-4652037-A1 | LAMINATED PARTS CONTAINING A HARD POLYURETHANE OUTER LAYER AND METHODS FOR THEIR PRODUCTION | Covestro LLC (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2025233647-A1 | BATTERY BOX COMPRISING A FOAMED POLISOCYANURATE MATERIAL | SIKA TECHNOLOGY AG (CH) | 2025-11-13 | — | — | WO | disclosed |
| EP-4638156-A1 | HYBRID COIL SPRING ISOLATOR | BASF SE (DE) | 2025-10-29 | — | — | EP | disclosed |
| US-12448552-B2 | Adhesive bond between a thermoplastic material and an elastomer composition | SIKA TECHNOLOGY AG (CH) | 2025-10-21 | — | — | US | disclosed |
| US-20250313681-A1 | SUBSTRATES WITH RESIN COMPOSITION ADHERED THERETO AND METHODS FOR IMPROVING ADHESION TO A SUBSTRATE | MOMENTIVE PERFORMANCE MAT INC (US) | 2025-10-09 | — | — | US | disclosed |
| WO-2025202053-A1 | CURABLE POLYURETHANE COMPOSITION WITH ISOCYANURATE SILANES | SIKA TECHNOLOGY AG (CH) | 2025-10-02 | — | — | WO | disclosed |
| EP-4624503-A1 | CURABLE POLYURETHANE COMPOSITION WITH ISOCYANURATE SILANES | Sika Technology AG (CH) | 2025-10-01 | — | — | EP | disclosed |
| US-4182829-A | Impression materials for dentistry | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-08 | — | — | US | disclosed |
| US-4156059-A | Inorganic-organic polymers and processes for their manufacture | CHEMIE-ANLAGENBAU BISCHOFSHEIM GMBH (DE) | 1979-05-22 | — | — | US | disclosed |
| US-4147680-A | Production of polyurethane resins using as active hydrogen material a stable dispersion of ionic polyisocyanate-polyaddition products in hydroxyl containing compounds as a dispersing agent | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-03 | — | — | US | disclosed |
| US-4128532-A | Polyetheresters which contain hydroxyl groups and the use thereof in the production of flame resistant synthetic resins | BAYER AKTIENGESELLSCHAFT (DE) | 1978-12-05 | — | — | US | disclosed |
| US-4123599-A | PHENOLIC RESINS REACTED WITH ORGANIC DIISOCYANATES AND/OR POLYISOCYANTES IN THE PRESENCE OF METAL POWDERS AND/OR METAL OXIDE POWDERS | CHEMIE-ANLAGENBAU BISCHOFSHEIM GMBH (DE) | 1978-10-31 | — | — | US | disclosed |
| US-4120923-A | Process for manufacturing foamed materials involving contacting a thin unbroken film of liquid resin with a gaseous blowing agent under pressure | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-17 | — | — | US | disclosed |
| US-4093569-A | Polyurethane resins produced from active hydrogen containing material which is a dispersion of polyisocyanate-polyaddition products in hydroxyl containing compounds as dispersing agents | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-06 | — | — | US | disclosed |
| US-4024090-A | Process for molding polyurethane foams | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-4013625-A | Process for the linearization of polyurethanes with lactams and lactam addition compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-3993606-A | Process for the production of polyurethane foams | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260005355-A1 | CURABLE POTTING MATERIAL FOR AUTOMOTIVE BATTERY PACKS | ACIN1, TCP1, TES | CYP1A2 2197/4885GAA 4347/4885MGAM 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.