Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PAICS | P22234 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792117 | 0.84 | GABRA5 (0.43) | KCNH2EPHX2GABRA5CNR2 | |
| SCHEMBL1996153 | 0.71 | SLC6A3 (0.71) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL1991200 | 0.71 | SLC6A3 (0.71) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL1991198 | 0.71 | SLC6A3 (0.71) | SLC6A3KCNH2TAAR1 | |
| Hydrochloric Acid SCHEMBL1995512 | 0.70 | SLC6A3 (0.70) | SLC6A3KCNH2TAAR1 | |
| Hydrochloric Acid SCHEMBL1989305 | 0.70 | SLC6A3 (0.70) | SLC6A3KCNH2TAAR1 | |
| Hydrochloric Acid SCHEMBL1989304 | 0.70 | SLC6A3 (0.70) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL1990594 | 0.68 | SLC6A3 (0.72) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL1989597 | 0.68 | SLC6A3 (0.72) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL1989594 | 0.68 | SLC6A3 (0.72) | SLC6A3KCNH2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |