Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794453 | 0.85 | MAPT (0.47) | SMN1; SMN2TDP1KDM4EALDH1A1GAA | |
| SCHEMBL27819990 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1TDP1ALDH1A1GAA | |
| SCHEMBL9726821 | 0.85 | MAPT (0.47) | SMN1; SMN2L3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL5796665 | 0.85 | TSHR (0.47) | SMN1; SMN2ALDH1A1EPHX2NPSR1MAPT | |
| SCHEMBL5794078 | 0.83 | MAPT (0.46) | SMN1; SMN2L3MBTL1TDP1ALDH1A1GAA | |
| SCHEMBL3268819 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2L3MBTL1TDP1ALDH1A1GAA | |
| SCHEMBL29114978 | 0.79 | CYP19A1 (0.55) | SMN1; SMN2L3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL5694726 | 0.78 | NPSR1 (0.50) | SMN1; SMN2TDP1KDM4EALDH1A1GAA | |
| SCHEMBL5694725 | 0.78 | NPSR1 (0.50) | SMN1; SMN2TDP1KDM4EALDH1A1GAA | |
| SCHEMBL9518987 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1TDP1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006013399-A1 | PHARMACEUTICAL INTERMEDIATES AND A PROCESS FOR THE PREPARATION THEREOF | EGIS Gyógyszergyár Rt. (HU) | 2006-02-09 | — | — | WO | disclosed |